Trends in integrated testing strategies for in vitro to in vivo extrapolation in chemical and drug safety for inhalation toxicology

Berube, Kelly Ann ORCID: https://orcid.org/0000-0002-7471-7229 2011. Trends in integrated testing strategies for in vitro to in vivo extrapolation in chemical and drug safety for inhalation toxicology. Biotech Online Magazine 22 , pp. 10-14.

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Abstract

The ideal is that all routine toxicity testing be undertaken in human-derived cells and tissues at the in vitro level. However models are needed that take account of metabolic and systemic reaction pathways for the better understanding of exposure parameters in vitro and their extrapolation to achieve safe exposure in vivo.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Biosciences
Subjects:	Q Science > Q Science (General)
Publisher:	Biotech International
Last Modified:	20 Oct 2022 08:25
URI:	https://orca.cardiff.ac.uk/id/eprint/28225

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