The organization of collagen in the corneal stroma

Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538 and Boote, Craig ORCID: https://orcid.org/0000-0003-0348-6547 2004. The organization of collagen in the corneal stroma. Experimental Eye Research 78 (3) , pp. 503-512. 10.1016/j.exer.2003.07.003

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Abstract

The cornea has evolved to fulfil the dual functions of enclosing and protecting the inner contents of the eye, and focussing light onto the retina with minimum scatter and optical degradation. It does this by means of the arrangement of the constituent collagen fibrils, an arrangement that is unique in connective tissues. This article reviews our current knowledge about the detailed organization of collagen in the corneal stroma, and presents new data suggesting that a significant proportion of collagen fibrils running across the cornea, change direction near the limbus and fuse with the circumferential limbal collagen.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Optometry and Vision Sciences
Subjects:	R Medicine > RE Ophthalmology
Uncontrolled Keywords:	cornea; stroma; limbus; collagen; proteoglycans; X-ray diffraction; microscopy
Publisher:	Elsevier
ISSN:	0014-4835
Last Modified:	20 Oct 2022 09:26
URI:	https://orca.cardiff.ac.uk/id/eprint/32016

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