Exposure to LHRH agonists in early pregnancy following the commencement of mid-luteal buserelin for IVF stimulation

Jackson, Anne E., Curtis, Paul, Amso, Nazar Najib ORCID: https://orcid.org/0000-0002-8646-6623 and Shaw, Robert W. 1992. Exposure to LHRH agonists in early pregnancy following the commencement of mid-luteal buserelin for IVF stimulation. Human Reproduction 7 (9) , pp. 1222-1224.

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Abstract

Exposure to buserelin in early pregnancy has been reported following its use in In-vitro fertilization treatment cycles. The number of reported cases is small. There are still no answers regarding embryotoxicity, and the need for luteal support is still unclear. A further six cases are reported here, five receiving luteal support and resulting in the delivery of healthy children, and one, without luteal support ending in a first trimester miscarriage. We propose that further data should be collected to allow adequate monitoring and follow-up of these pregnancies.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > R Medicine (General) R Medicine > RG Gynecology and obstetrics
Uncontrolled Keywords:	embryotoxicity; TVF; LHRH agonists; pregnancy
Publisher:	Oxford University Press
ISSN:	0268-1161
Last Modified:	21 Oct 2022 08:44
URI:	https://orca.cardiff.ac.uk/id/eprint/34272

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