Warburton, E. C., Morgan, A., Baird, Alison Lambie, Muir, Janice L. and Aggleton, John Patrick ![]() |
Abstract
Rats that had been pretrained on 2 tests of allocentric memory (water maze and T maze) received bilateral cytotoxic lesions in the anterior thalamic nuclei (ATN) or transection of the fimbria-fornix (FF). After surgery, both groups of rats were impaired on both tasks, although the preoperative training resulted in a rapid initial reacquisition of the water maze task. Those rats with lesions largely restricted to the ATN were impaired at a level comparable to that produced by FF lesions. This finding is consistent with a close functional relationship between the hippocampus and the ATN, necessary for the acquisition and on-line processing of allocentric spatial information but not for the maintenance/retrieval of procedural information. The rats with more extensive thalamic lesions were more impaired in both tasks and did show a loss of procedural information.
Item Type: | Article |
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Date Type: | Publication |
Status: | Published |
Schools: | Schools > Biosciences Schools > Psychology Schools > Medicine Research Institutes & Centres > Neuroscience and Mental Health Research Institute (NMHII) |
Subjects: | B Philosophy. Psychology. Religion > BF Psychology R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry |
Publisher: | American Psychological Association |
ISSN: | 0735-7044 |
Last Modified: | 21 Oct 2022 08:58 |
URI: | https://orca.cardiff.ac.uk/id/eprint/34927 |
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