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Chemoenzymatic preparation of germacrene analogues

Cascón, Oscar, Touchet, Sabrina, Miller, David James, Gonzalez, Veronica, Faraldos, Juan A. and Allemann, Rudolf Konrad ORCID: https://orcid.org/0000-0002-1323-8830 2012. Chemoenzymatic preparation of germacrene analogues. Chemical Communications 48 (78) , pp. 9702-9704. 10.1039/c2cc35542f

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Abstract

A small library of novel germacrenes was generated using a combination of two plant enzymes, germacrene A synthase, and D synthase and modified farnesyl diphosphate (FDP) analogues. This chemoenzymatic approach allows the preparation of potentially valuable volatiles for biological studies.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Chemistry
Cardiff Catalysis Institute (CCI)
Subjects: Q Science > QD Chemistry
Publisher: RSC Publishing
ISSN: 1359-7345
Funders: BBSRC
Date of First Compliant Deposit: 30 March 2016
Last Modified: 08 Jan 2024 07:32
URI: https://orca.cardiff.ac.uk/id/eprint/37170

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