Management of suspected viral encephalitis in adults - Association of British Neurologists and British Infection Association National Guidelines

Solomon, T., Michael, B. D., Smith, Philip E. M. ORCID: https://orcid.org/0000-0003-4250-2562, Sanderson, F., Davies, N. W. S., Hart, I. J., Holland, M., Easton, A., Buckley, C., Kneen, R. and Beeching, N. J. 2012. Management of suspected viral encephalitis in adults - Association of British Neurologists and British Infection Association National Guidelines. Journal of Infection 64 (4) , pp. 347-373. 10.1016/j.jinf.2011.11.014

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Abstract

In the 1980s the outcome of patients with herpes simplex encephalitis was shown to be dramatically improved with aciclovir treatment. Delays in starting treatment, particularly beyond 48 h after hospital admission, are associated with a worse prognosis. Several comprehensive reviews of the investigation and management of encephalitis have been published. However, their impact on day-to day clinical practice appears to be limited. The emergency management of meningitis in children and adults was revolutionised by the introduction of a simple algorithm as part of management guidelines. In February 2008 a group of clinicians met in Liverpool to begin the development process for clinical care guidelines based around a similar simple algorithm, supported by an evidence base, whose implementation is hoped would improve the management of patients with suspected encephalitis.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine Neuroscience and Mental Health Research Institute (NMHRI)
Subjects:	R Medicine > R Medicine (General)
Uncontrolled Keywords:	encephalitis, viral encephalitis, herpes simplex virus, immunocompromised, varicella zoster virus, enterovirus, antibody-associated encephalitis
Publisher:	Elsevier
ISSN:	0163-4453
Last Modified:	21 Oct 2022 10:43
URI:	https://orca.cardiff.ac.uk/id/eprint/41116

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