Relative prognostic value of human epidermal growth factor receptor 2 (HER2) expression in operable oesophagogastric cancer

Chan, David, Campbell, Fiona, Edwards, Paul, Jasani, Bharat, Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940 and Lewis, Wyn G. 2012. Relative prognostic value of human epidermal growth factor receptor 2 (HER2) expression in operable oesophagogastric cancer. ISRN Surgery 2012 10.5402/2012/804891

Preview

PDF - Published Version Available under License Creative Commons Attribution. Download (1MB) | Preview

Abstract

Aims. The aim of this study was to determine the prognostic significance of HER2 receptor expression in operable oesophagogastric adenocarcinoma. Methods. Eighty-five consecutive patients diagnosed with oesophagogastric adenocarcinoma [18 oesophageal (OC), 32 junctional (JC) and 35 gastric (GC)] undergoing potentially curative resection were studied retrospectively. Immunohistochemistry was used to determine HER2 status at endoscopic biopsy and resection specimen. The primary outcome measure was survival. Results. Twenty (24%) patients had HER2 positive tumours which was commoner in JC (14/32, 44% versus 2/18, 11% in OC and 4/35, 11% in GC,

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Publisher:	Hindawi Publishing Group
ISSN:	2090-5793
Date of First Compliant Deposit:	30 March 2016
Last Modified:	09 Jul 2024 07:02
URI:	https://orca.cardiff.ac.uk/id/eprint/43644

Citation Data

Actions (repository staff only)

Edit Item