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Number of items: 37.

Meuser, Elena, Chang, Kyle, Walters, Angharad, Hurley, Joanna J., West, Hannah D. ORCID: https://orcid.org/0000-0002-6104-6534, Perry, Iain, Mort, Matthew, Reyes-Uribe, Laura, Truscott, Rebekah, Jones, Nicholas, Lawrence, Rachel, Jenkins, Gareth, Giles, Peter ORCID: https://orcid.org/0000-0003-3143-6854, Dolwani, Sunil ORCID: https://orcid.org/0000-0002-3113-5472, Al-Sarireh, Bilal, Hawkes, Neil, Short, Emma, Williams, Geraint T. ORCID: https://orcid.org/0000-0003-3768-9940, Taggart, Melissa W., Luetchford, Kim, Lynch, Patrick M., Terlouw, Diantha, Nielsen, Maartje, Walton, Sarah-Jane, Latchford, Andrew, Clark, Susan K., Sampson, Julian R. ORCID: https://orcid.org/0000-0002-2902-2348, Vilar, Eduardo and Thomas, Laura E. 2024. PIGA mutations and glycosylphosphatidylinositol anchor dysregulation in polyposis-associated duodenal tumorigenesis. Molecular Cancer Research 22 (6) , 515–523. 10.1158/1541-7786.MCR-23-0810
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Greenow, Kristy R., Zverev, Matthew, May, Stephanie, Kendrick, Howard, Williams, Geraint T. ORCID: https://orcid.org/0000-0003-3768-9940, Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916 and Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 2018. Lect2 deficiency is characterised by altered cytokine levels and promotion of intestinal tumourigenesis. Oncotarget 9 (92) , pp. 36430-36443. 10.18632/oncotarget.26335
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Hurley, Joanna J., Thomas, Laura E. ORCID: https://orcid.org/0000-0002-8621-5285, Walton, Sarah-Jane, Thomas-Gibson, Siwan, Haycock, Adam, Suzuki, Noriko, Mort, Matthew ORCID: https://orcid.org/0000-0002-3986-0935, Williams, Geraint ORCID: https://orcid.org/0000-0003-3768-9940, Morgan, Meleri, Clark, Susan K., Sampson, Julian R. ORCID: https://orcid.org/0000-0002-2902-2348 and Dolwani, Sunil ORCID: https://orcid.org/0000-0002-3113-5472 2018. The impact of chromoendoscopy for surveillance of the duodenum in patients with MUTYH-associated polyposis and familial adenomatous polyposis. Gastrointestinal Endoscopy 88 (4) , pp. 665-673. 10.1016/j.gie.2018.04.2347
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Thomas, Laura E. ORCID: https://orcid.org/0000-0002-8621-5285, Hurley, Joanna J., Meuser, Elena, Jose, Sian, Ashelford, Kevin E. ORCID: https://orcid.org/0000-0003-3217-2811, Mort, Matthew ORCID: https://orcid.org/0000-0002-3986-0935, Idziaszczyk, Shelley, Maynard, Julie, Leon Brito, Helena, Harry, Manon, Walters, Angharad, Raja, Meera, Walton, Sarah-Jane, Dolwani, Sunil ORCID: https://orcid.org/0000-0002-3113-5472, Williams, Geraint T. ORCID: https://orcid.org/0000-0003-3768-9940, Morgan, Meleri, Moorghen, Morgan, Clark, Susan K. and Sampson, Julian R. ORCID: https://orcid.org/0000-0002-2902-2348 2017. Burden and profile of somatic mutation in duodenal adenomas from patients with familial adenomatous- and MUTYH-associated polyposis. Clinical Cancer Research 23 (21) , pp. 6721-6732. 10.1158/1078-0432.CCR-17-1269
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Griggs, Rebecca K. L., Novelli, Marco R., Sanders, D. Scott A., Warren, Bryan F., Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940, Quirke, Philip and Shepherd, Neil A. 2017. Challenging diagnostic issues in adenomatous polyps with epithelial misplacement in bowel cancer screening: 5 years' experience of the Bowel Cancer Screening Programme Expert Board. Histopathology 70 (3) , pp. 466-472. 10.1111/his.13092

Jezkova, Jana, Williams, J. S., Pinto, F., Sammut, Stephen, Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940, Gollins, Simon, McFarlane, R. J., Reis, R. M. and Wakeman, J. A. 2016. Brachyury identifies a class of enteroendocrine cells in normal human intestinal crypts and colorectal cancer. Oncotarget 7 , pp. 11478-11486. 10.18632/oncotarget.7202
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Rashid, Mamunur, Fischer, Andrej, Wilson, Cathy H., Tiffen, Jessamy, Rust, Alistair G., Stevens, Philip, Idziaszczyk, Shelley, Maynard, Julie, Williams, Geraint T. ORCID: https://orcid.org/0000-0003-3768-9940, Mustonen, Ville, Sampson, Julian R. ORCID: https://orcid.org/0000-0002-2902-2348 and Adams, David J. 2016. Adenoma development in familial adenomatous polyposis andMUTYH-associated polyposis: somatic landscape and driver genes. Journal of Pathology 238 (1) , pp. 98-108. 10.1002/path.4643
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Costa Bento, Diana Filipa, Jones, Emma, Junaid, Syed, Tull, Justyna, Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567, Ager, Ann and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2015. High endothelial venules are rare in colorectal cancers but accumulate in extra-tumoral areas with disease progression. OncoImmunology 4 (3) , pp. 653-660. 10.4161/2162402X.2014.974374
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Greenow, K. R., Clarke, A. R. ORCID: https://orcid.org/0000-0002-4281-426X, Williams, G. T. ORCID: https://orcid.org/0000-0003-3768-9940 and Jones, R. ORCID: https://orcid.org/0000-0003-3576-9496 2014. Wnt-driven intestinal tumourigenesis is suppressed by Chk1 deficiency but enhanced by conditional haploinsufficiency. Oncogene 33 , pp. 4089-4096. 10.1038/onc.2013.371

Holik, Aliaksei Z., Young, Madeleine, Krzystyniak, Joanna, Williams, Geraint T. ORCID: https://orcid.org/0000-0003-3768-9940, Metzger, Daniel, Shorning, Boris Y. and Clarke, Alan R. ORCID: https://orcid.org/0000-0002-4281-426X 2014. Brg1 loss attenuates aberrant Wnt-signalling and prevents Wnt-dependent tumourigenesis in the murine small intestine. PLoS Genetics 10 (7) , e1004453. 10.1371/journal.pgen.1004453
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Davies, Emma Jane, Marsh Durban, Victoria ORCID: https://orcid.org/0000-0003-1645-1618, Meniel, Valerie, Williams, Geraint Trfor ORCID: https://orcid.org/0000-0003-3768-9940 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2014. PTEN loss and KRAS activation leads to the formation of serrated adenomas and metastatic carcinoma in the mouse intestine. The Journal of Pathology 233 (1) , pp. 27-38. 10.1002/path.4312

Maughan, T.S., Meade, A.M., Adams, R. A. ORCID: https://orcid.org/0000-0003-3915-7243, Richman, S.D., Butler, R., Fisher, D., Wilson, R.H., Jasani, B., Taylor, G.R., Williams, G. ORCID: https://orcid.org/0000-0003-3768-9940, Sampson, J. ORCID: https://orcid.org/0000-0002-2902-2348, Seymour, M.T., Nichols, L.L., Kenny, S.L., Nelson, A. ORCID: https://orcid.org/0000-0002-6075-8425, Sampson, C. ORCID: https://orcid.org/0000-0002-5626-9936, Hodgkinson, E., Bridgewater, J.A., Furniss, D.L., Roy, R., Pope, M.J., Pope, J.K., Parmar, M., Quirke, P. and Kaplan, R. 2014. A feasibility study testing four hypotheses with phase II outcomes in advanced colorectal cancer (MRC FOCUS3): A model for randomised controlled trials in the era of personalised medicine? British Journal of Cancer 110 , pp. 2178-2186. 10.1038/bjc.2014.182
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Fielding, Ceri A. ORCID: https://orcid.org/0000-0002-5817-3153, Jones, Gareth W. ORCID: https://orcid.org/0000-0001-7297-9711, McLoughlin, Rachel M., McLeod, Louise, Hammond, Victoria J., Uceda, Javier, Williams, Anwen S. ORCID: https://orcid.org/0000-0003-3768-9940, Lambie, Mark, Foster, Thomas L., Liao, Chia-Te, Rice, Christopher M., Greenhill, Claire J., Colmont, Chantal S., Hams, Emily ORCID: https://orcid.org/0000-0002-9745-3246, Coles, Barbara, Kift-Morgan, Ann, Newton, Zarabeth, Craig, Katherine J., Williams, John D. ORCID: https://orcid.org/0000-0003-3768-9940, Williams, Geraint T. ORCID: https://orcid.org/0000-0003-3768-9940, Davies, Simon J., Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337, O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460, Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421, Jenkins, Brendan J., Topley, Nicholas and Jones, Simon A. ORCID: https://orcid.org/0000-0001-7297-9711 2014. Interleukin-6 signaling drives fibrosis in unresolved inflammation. Immunity 40 (1) , pp. 40-50. 10.1016/j.immuni.2013.10.022
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Roger, Laureline, Jones, Rhiannon E., Heppel, Nicole, Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940, Sampson, Julian Roy ORCID: https://orcid.org/0000-0002-2902-2348 and Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467 2013. Extensive telomere erosion in the initiation of colorectal adenomas and its association with chromosomal instability. Journal of the National Cancer Institute 105 (16) , pp. 1202-1211. 10.1093/jnci/djt191

Marsh Durban, Victoria ORCID: https://orcid.org/0000-0003-1645-1618, Davies, Emma Jane, Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2013. PTEN loss and KRAS activation cooperate in murine biliary tract malignancies. The Journal of Pathology 230 (2) , pp. 165-173. 10.1002/path.4189

Turner, Jeffrey Keith, Wright, Melissa ORCID: https://orcid.org/0000-0002-1011-4795, Morgan, Meleri, Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940 and Dolwani, Sunil ORCID: https://orcid.org/0000-0002-3113-5472 2013. A prospective study of the accuracy and concordance between in-situ and postfixation measurements of colorectal polyp size and their potential impact upon surveillance. European Journal of Gastroenterology & Hepatology 25 (5) , pp. 562-567. 10.1097/MEG.0b013e32835d1f2d

Turner, Jeffrey, Williams, Geraint ORCID: https://orcid.org/0000-0003-3768-9940, Morgan, Meleri, Wright, Melissa ORCID: https://orcid.org/0000-0002-1011-4795 and Dolwani, Sunil ORCID: https://orcid.org/0000-0002-3113-5472 2013. Interobserver agreement in the reporting of colorectal polyp pathology among bowel cancer screening pathologists in Wales. Histopathology 62 (6) , pp. 916-924. 10.1111/his.12110

Meniel, Valerie, Song, Fei, Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Young, Madeleine, Poetz, Oliver, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Jenkins, John R., Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940, Dunwoodie, Sally L., Watson, Alastair and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2013. Cited1 deficiency suppresses intestinal tumorigenesis. PLoS Genetics 9 (8) , e1003638. 10.1371/journal.pgen.1003638
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Feng, Gui Jie, Cotta, Welwyn, Wei, Xiao-Qing ORCID: https://orcid.org/0000-0002-6274-8503, Poetz, Oliver, Evans, Rebecca Jane, Jardé, Thierry, Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Meniel, Valerie, Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2012. Conditional disruption of Axin1 leads to development of liver tumors in mice. Gastroenterology 143 (6) , pp. 1650-1659. 10.1053/j.gastro.2012.08.047

Chan, David, Campbell, Fiona, Edwards, Paul, Jasani, Bharat, Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940 and Lewis, Wyn G. 2012. Relative prognostic value of human epidermal growth factor receptor 2 (HER2) expression in operable oesophagogastric cancer. ISRN Surgery 2012 10.5402/2012/804891
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Betts, Gareth James, Jones, Emma, Junaid, Syed, El-Shanawany, Tariq, Scurr, Martin John ORCID: https://orcid.org/0000-0002-4120-0688, Mizen, Paul Edward, Kumar, Mayur, Jones, Sion, Rees, Brian Idris, Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 2012. Suppression of tumour-specific CD4+ T cells by regulatory T cells is associated with progression of human colorectal cancer. Gut 61 (8) , pp. 1163-1171. 10.1136/gutjnl-2011-300970

Reid, Thomas D., Sanyaolu, Leigh N. ORCID: https://orcid.org/0000-0002-6762-6986, Chan, David, Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940 and Lewis, W. G. 2011. Relative prognostic value of TNM7 vs TNM6 in staging oesophageal cancer. British Journal of Cancer 105 (6) , pp. 842-846. 10.1038/bjc.2011.320

Ramadas, Arvind Venkatesh, Gunesh, Sanjiv Kumar, Thomas, G. A. O., Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940 and Hawthorne, A. B. 2010. Natural history of Crohn's disease in a population-based cohort from Cardiff (1986-2003): a study of changes in medical treatment and surgical resection rates. Gut 59 (9) , pp. 1200-1206. 10.1136/gut.2009.202101

Zimbwa, Truman Austin, Owen, R., Thomas, G., Hargest, Rachel ORCID: https://orcid.org/0000-0001-9830-3832 and Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940 2010. An unusual complication of colitis. Gut 59 (3) , p. 364. 10.1136/gut.2009.179689

Dallosso, Anthony Richard, Jones, Siân, Azzopardi, Duncan Lee, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Al-Tassan, Nada A., Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940, Idziaszczyk, Shelley Alexis, Davies, D. Rhodri, Milewski, Peter, Williams, Sally, Beynon, John, Sampson, Julian Roy ORCID: https://orcid.org/0000-0002-2902-2348 and Cheadle, Jeremy Peter ORCID: https://orcid.org/0000-0001-9453-8458 2009. The APC Variant p.Glu1317Gln predisposes to colorectal adenomas by a novel mechanism of relaxing the target for tumorigenic somatic APC mutations. Human Mutation 30 (10) , pp. 1412-1418. 10.1002/humu.21089

Twine, Christopher P. ORCID: https://orcid.org/0000-0003-0385-5760, Lewis, Wyn G., Morgan, Matthew A., Chan, David, Clark, Geoffrey William Barton, Havard, Tim, Crosby, Thomas David Lewis, Roberts, S. Ashley and Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940 2009. The assessment of prognosis of surgically resected oesophageal cancer is dependent on the number of lymph nodes examined pathologically. Histopathology 55 (1) , pp. 46-52. 10.1111/j.1365-2559.2009.03332.x

Maguire, Aoife A., Greenson, Joel K., Lauwers, Greg Y., Ginsburg, Richard E., Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940, Brown, Ian S., Riddell, Robert H., O'Donoghue, Diarmuid and Sheahan, Kieran D. 2009. Collagenous sprue: a clinicopathologic study of 12 cases. The American Journal of Surgical Pathology 33 (10) , pp. 1440-1449. 10.1097/PAS.0b013e3181ae2545

Marsh Durban, Victoria ORCID: https://orcid.org/0000-0003-1645-1618, Winton, Douglas J., Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940, Dubois, Nicole, Trumpp, Andreas, Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2008. Epithelial Pten is dispensable for intestinal homeostasis but suppresses adenoma development and progression after Apc mutation. Nature Genetics 40 (12) , pp. 1436-1444. 10.1038/ng.256

Dolwani, Sunil ORCID: https://orcid.org/0000-0002-3113-5472, Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940, West, K.P., Newman, J., Stock, D., Williams, A.P., Best, J., Cheadle, Jeremy Peter ORCID: https://orcid.org/0000-0001-9453-8458 and Sampson, Julian Roy ORCID: https://orcid.org/0000-0002-2902-2348 2007. Analysis of inherited MYH (MUTYH) mutations in British Asian patients with colorectal cancer [Letter]. Gut 56 (4) , p. 593. 10.1136/gut.2006.094532

Hughes, Lisa, Palmer-Smith, S., Rogers, M. T., Frayling, Ian Martin, Stephens, M., Rosser, L., Jasani, Bharat, Williams, Geraint ORCID: https://orcid.org/0000-0003-3768-9940 and Jasani, B. 2006. Investigation of an HNPCC mutation of unknown significance - A clinical and laboratory perspective [Abstract]. Journal of Medical Genetics 43 (Supp.) , S73.

Goodwin, Richard G., Kell, William Jonathan, Laidler, Peter, Long, C. Colin, Whatley, Sharon D., McKinley, Mark, Badminton, Michael Norman, Burnett, Alan Kenneth, Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940 and Elder, George Hill 2006. Photosensitivity and acute liver injury in myeloproliferative disorder secondary to late-onset protoporphyria caused by deletion of a ferrochelastase gene in hematopoietic cells. Blood 107 (1) , pp. 60-62. 10.1182/blood-2004-12-4939

Jones, Sian, Lambert, S., Williams, Geraint Trevor ORCID: https://orcid.org/0000-0003-3768-9940, Best, J. M., Sampson, Julian Roy ORCID: https://orcid.org/0000-0002-2902-2348 and Cheadle, Jeremy Peter ORCID: https://orcid.org/0000-0001-9453-8458 2004. Increased frequency of the k-ras G12C mutation in MYH polyposis colorectal adenomas. British Journal of Cancer 90 (8) , pp. 1591-1593. 10.1038/sj.bjc.6601747
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Williams, John David, Craig, Kathrine Jane, Von Ruhland, Christopher John, Topley, Nicholas and Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940 2003. The natural course of peritoneal membrane biology during peritoneal dialysis. Kidney International 64 (s88) , SS43-SS49. 10.1046/j.1523-1755.2003.08805.x

Williams, John David, Craig, Kathrine Jane, Topley, Nicholas and Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940 2003. Peritoneal dialysis: changes to the structure of the peritoneal membrane and potential for biocompatible solutions. Kidney International 63 (s84) , S158-S161. 10.1046/j.1523-1755.63.s84.46.x

Jones, Sian, Emmerson, Paul, Maynard, Julie Helen, Best, Jacqueline M., Jordan, Sheila, Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940, Sampson, Julian Roy ORCID: https://orcid.org/0000-0002-2902-2348 and Cheadle, Jeremy Peter ORCID: https://orcid.org/0000-0001-9453-8458 2002. Biallelic germline mutations in MYH predispose to multiple colorectal ademona and somatic G:C to T:A mutations. Human Molecular Genetics 11 (23) , pp. 2961-2967. 10.1093/hmg/11.23.2961

Williams, John David, Craig, Kathrine Jane, Topley, Nicholas, Von Ruhland, Christopher John, Fallon, Maureen, Newman, Geoffrey Richard, MacKenzie, Ruth Kathryn and Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940 2002. Morphologic changes in the peritoneal membrane of patients with renal disease. Journal of the American Society of Nephrology 13 (2) , pp. 470-479.

Al-Tassan, Nada ORCID: https://orcid.org/0000-0001-9453-8458, Chmiel, Nikolas H., Maynard, Julie Helen, Fleming, Nick, Livingston, Alison L., Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940, Hodges, Angela Kaye, Davies, D.Rhodri, David, Sheila S., Sampson, Julian Roy ORCID: https://orcid.org/0000-0002-2902-2348 and Cheadle, Jeremy Peter ORCID: https://orcid.org/0000-0001-9453-8458 2002. Inherited variants of MYH associated with somatic G:C to T:A mutations in colorectal tumors. Nature Genetics 30 (2) , pp. 227-32. 10.1038/ng828

This list was generated on Fri Feb 21 06:15:07 2025 GMT.


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