Factors contributing to the survival of a strain of Pseudomonas cepacia in chlorhexidine solutions

Hugo, W. B., Pallent, L. J., Grant, D. J. W., Denyer, Stephen Paul and Davies, A. 1986. Factors contributing to the survival of a strain of Pseudomonas cepacia in chlorhexidine solutions. Letters in Applied Microbiology 2 (3) , pp. 37-42. 10.1111/j.1472-765X.1986.tb01511.x

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Abstract

Adsorption of Pseudomonas cepacia onto the surface of glass containers enables cells to survive in the presence of user strength chlorhexidine (0.05% w/v). The organisms were found to be firmly attached to the glass and colonised glass slides could be used to infect uncontaminated chlorhexidine solutions. The efficacy of chlorhexidine against Ps. cepacia decreased with decreasing pH. Storing infected solutions at low temperatures reduced the toxicity of chlorhexidine and promoted longer survival.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Pharmacy Neuroscience and Mental Health Research Institute (NMHRI)
Subjects:	Q Science > QR Microbiology R Medicine > RM Therapeutics. Pharmacology
Publisher:	Wiley-Blackwell
ISSN:	1472-765X
Last Modified:	19 Mar 2016 23:14
URI:	https://orca.cardiff.ac.uk/id/eprint/44228

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