The effects of protective occlusive gloves on stratum corneum barrier properties

Graves, Christopher, Edwards, C. and Marks, R. 1995. The effects of protective occlusive gloves on stratum corneum barrier properties. Contact Dermatitis 33 (3) , pp. 183-187. 10.1111/j.1600-0536.1995.tb00542.x

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Abstract

Data suggests that protection From gloves is paradoxically reduced became of effects of occlusion on the skin. The aim of this study was to characterize these effects on physical and functional properties of stratum corneum. Volunteer trials were conducted using patches of polyvinyl chloride (PVC) glove material on the skin. Impairment of barrier function -was assessed by measuring transepidermal water loss (TEWL). Hydration and water sorption-desorption was assessed using skin conductance. The major finding was a short-term impairment of barrier function, measured as an increase in TEWL of 1.7 gn −2 h −1 (95% C.I. 0.4 to 2.6 gn −2, h −1, p < 0.01) Temporary increases in hydration and water sorption were also observed. On this basis, the effects of wearing PVC gloves over 2 days on stratum corneum barrier properties on the dorsum of the hand were studied. TEWL measurements remained elevated by 1.5 gn −2 h −1 the day after occlude glove removal (95% C.I 0.2 to 2.8 gn −2 h −1, p < 0.01), indicating a possible cumulative effect. In conclusion, our studies demonstrate a potential hazard resulting from the repeated use of protective gloves.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine University IT
Subjects:	R Medicine > R Medicine (General) R Medicine > RL Dermatology
Uncontrolled Keywords:	skin occlusion; protective gloves; transepidermal water loss; skin barrier function; electrical conductance; prevention; occupational dermatitis; PVC glove material; bioengineering methods
Publisher:	Wiley-Blackwell
ISSN:	0105-1873
Last Modified:	13 Jan 2023 04:04
URI:	https://orca.cardiff.ac.uk/id/eprint/45152

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