Arany, A., Crowley, P. J., Fawcett, J., Hursthouse, M. B., Kariuki, Benson ![]() |
Official URL: http://dx.doi.org/10.1039/B314314G
Abstract
A difluorodienophile, synthesised using a Stille coupling reaction underwent tin(IV)-catalysed cycloaddition with three furans to afford oxa[2.2.1]bicycloheptenes in good yield. Reduction of ester and carbamate carbonyl groups and diol protection as the acetonide set the stage for palladium-catalysed hydrostannylation in two cases. Treatment of the stannanes with methyllithium triggered ring-opening to afford highly-functionalised difluorinated cyclohexenols which could be deprotected to afford (hydroxymethyl)conduritol analogues.
Item Type: | Article |
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Date Type: | Publication |
Status: | Published |
Schools: | Chemistry |
Subjects: | Q Science > QD Chemistry |
Publisher: | Royal Society of Chemistry |
Last Modified: | 24 Oct 2022 11:11 |
URI: | https://orca.cardiff.ac.uk/id/eprint/47209 |
Citation Data
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