Dinuclear double-stranded metallosupramolecular ruthenium complexes: Potential anticancer drugs

Hotze, Anna C. G., Kariuki, Benson ORCID: https://orcid.org/0000-0002-8658-3897 and Hannon, Michael J. 2006. Dinuclear double-stranded metallosupramolecular ruthenium complexes: Potential anticancer drugs. Angewandte Chemie International Edition 45 (29) , pp. 4839-4842. 10.1002/anie.200601351

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Abstract

Just add a twist: Metallosupramolecular architecture design is used to create anti-cancer agents with high activities in human breast cancer cell lines. Three isomers, which comprise a nonhelical metallocyclophane, an unsaturated double helicate, and a new type of double helicate, bridge the fields of metallosupramolecular architecture and anticancer drug design (picture: double-helical trans/cis isomer; red Ru, green Cl).

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Schools > Chemistry
Subjects:	Q Science > QD Chemistry R Medicine > RM Therapeutics. Pharmacology
Publisher:	Wiley-Blackwell
Last Modified:	24 Oct 2022 11:11
URI:	https://orca.cardiff.ac.uk/id/eprint/47235

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