Plasma electrolytes in elderly patients taking fixed combination diuretic

Bayer, Antony James ORCID: https://orcid.org/0000-0002-7514-248X, Farag, R., Browne, S. and Pathy, M. S. 1986. Plasma electrolytes in elderly patients taking fixed combination diuretic. Postgraduate Medical Journal 62 (725) , pp. 159-162. 10.1136/pgmj.62.725.159

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Abstract

Plasma potassium and sodium concentrations were measured in a group of elderly patients taking maintenance thiazide diuretic therapy alone, with a potassium supplement or in combination with a potassium sparing diuretic. Fixed dose combinations of a thiazide and potassium sparing diuretic did not significantly reduce the prevalence of hypokalaemia and the combination of amiloride-hydrochlorothiazide was associated with a disproportionate number of cases of hyponatraemia. The desirability of the current widespread use of fixed dose combination diuretics over less expensive single agents is questioned.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > R Medicine (General)
Publisher:	BMJ Publishing Group
ISSN:	0032-5473
Last Modified:	24 Oct 2022 11:46
URI:	https://orca.cardiff.ac.uk/id/eprint/49282

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