Watt, A. H., Bayer, Antony James ORCID: https://orcid.org/0000-0002-7514-248X, Routledge, Philip Alexander and Swift, C. G. 1989. Adenosine-induced respiratory and heart rate changes in young and elderly adults. British Journal of Clinical Pharmacology 27 (2) , pp. 265-267. 10.1111/j.1365-2125.1989.tb05360.x |
Official URL: http://dx.doi.org/10.1111/j.1365-2125.1989.tb05360...
Abstract
The effects of intravenous boluses of adenosine on respiration and heart rate were compared in young and elderly individuals. Respiratory stimulation and biphasic changes in heart rate were confirmed. The dose-response relationship for the effects of adenosine on respiration and heart-rate did not differ significantly between 10 young (mean age 25.2 + 4.9 years) and 10 elderly (mean age 66 ± 3.1 years) drug-free individuals, indicating that age is unlikely to be a major determinant of adenosine responsiveness.
Item Type: | Article |
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Date Type: | Publication |
Status: | Published |
Schools: | Medicine |
Subjects: | R Medicine > RM Therapeutics. Pharmacology |
Uncontrolled Keywords: | adenosine, age, respiration, heart rate |
Publisher: | Wiley-Blackwell |
ISSN: | 0306-5251 |
Last Modified: | 24 Oct 2022 12:00 |
URI: | https://orca.cardiff.ac.uk/id/eprint/50065 |
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