The NAC domain transcription factors FEZ and SOMBRERO control the orientation of cell division plane in Arabidopsis root stem cells

Willemsen, Viola, Bauch, Marion, Bennett, Tom, Campilho, Ana, Wolkenfelt, Harald, Xu, Jian, Haseloff, Jim and Scheres, Ben ORCID: https://orcid.org/0000-0001-5400-9578 2008. The NAC domain transcription factors FEZ and SOMBRERO control the orientation of cell division plane in Arabidopsis root stem cells. Developmental Cell 15 (6) , pp. 913-922. 10.1016/j.devcel.2008.09.019

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Abstract

Because plant cells do not migrate, cell division planes are crucial determinants of plant cellular architecture. In Arabidopsis roots, stringent control of cell divisions leads to a virtually invariant division pattern, including those that create new tissue layers. However, the mechanisms that control oriented cell divisions are hitherto poorly understood. Here, we reveal one such mechanism in which FEZ and SOMBRERO (SMB), two plant-specific NAC-domain transcription factors, control the delicately tuned reorientation and timing of cell division in a subset of stem cells. FEZ is expressed in root cap stem cells, where it promotes periclinal, root cap-forming cell divisions. In contrast, SMB negatively regulates FEZ activity, repressing stem cell-like divisions in the root cap daughter cells. FEZ becomes expressed in predivision stem cells, induces oriented cell division, and activates expression of its negative regulator, SMB, thus generating a feedback loop for controlled switches in cell division plane.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Biosciences
Subjects:	Q Science > QH Natural history > QH301 Biology
Uncontrolled Keywords:	Cellbio; Stemcell
Publisher:	Elsevier
ISSN:	1534-5807
Last Modified:	25 Oct 2022 08:14
URI:	https://orca.cardiff.ac.uk/id/eprint/51920

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