Expression of csal1 in pre limb-bud chick embryos

Sweetman, Dylan, Smith, Terence Gordon, Farrell, Elizabeth R. and Munsterberg, Andrea 2005. Expression of csal1 in pre limb-bud chick embryos. International Journal of Developmental Biology 49 (4) , pp. 427-430. 10.1387/ijdb.051985ds

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Abstract

The spalt family of transcriptional repressors has been implicated in limb, heart, ear and kidney development and truncating mutations in a human gene, SALL1, result in the autosomal dominant disorder Townes-Brocks syndrome. Here we show the expression pattern of the chick orthologue of the SALL1 gene, csal1, during early development. We found csal1 expression in the heart and in the pharynx, a source of inductive signals during heart development. Expression was also seen in involuting mesoderm and later in presegmented paraxial mesoderm. We also describe expression in the ectoderm and neural plate of the early embryo and subsequent expression in the neural tube. Keywords: chick, csal1, Townes-Brocks syndrome, spalt, heart

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Optometry and Vision Sciences
Subjects:	Q Science > QH Natural history > QH301 Biology R Medicine > RE Ophthalmology
Additional Information:	Pdf uploaded in accordance with publisher's policy at http://www.ijdb.ehu.es/web/descarga/instructions (accessed 27/02/2014).
Publisher:	University of the Basque Country press
ISSN:	0214-6282
Funders:	Medical Research Council
Date of First Compliant Deposit:	30 March 2016
Last Modified:	02 May 2023 17:49
URI:	https://orca.cardiff.ac.uk/id/eprint/53373

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