On the synthesis of furan-containing fragrance compounds

King, Ian Stephen Charles 2011. On the synthesis of furan-containing fragrance compounds. PhD Thesis, Cardiff University.

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Abstract

This thesis describes the use of both silver nitrate, and iodine, to promote 5-endo-dig cyclisations for the formation of furans. The synthesis of kahweofuran and other furan-containing fragrance compounds is described, along with an investigation into the selectivity of the 5-endo-dig cyclisation process. Chapter 2 describes the synthesis of furan-containing analogues of known fragrance compounds using a silver-catalysed cyclisation methodology. The analysis of some of these compounds by an "expert nose" is discussed. Chapter 3 describes the synthesis of kahweofuran, a furan-containing compound reported to be one of the major odour constituents of roasted coffee. Chapter 4 describes an investigation into the cyclisation of triols upon exposure to silver nitrate or iodine when more than one cyclisation pathway is possible.

Item Type:	Thesis (PhD)
Status:	Unpublished
Schools:	Chemistry
Subjects:	Q Science > QD Chemistry
ISBN:	9781303222818
Date of First Compliant Deposit:	30 March 2016
Last Modified:	19 Mar 2016 23:31
URI:	https://orca.cardiff.ac.uk/id/eprint/55118

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