Long-term brain impairment in chronic alcoholics: N2-P3 cognitive potentials in a template-matching memory task

Ciesielski, K. T., Madden, J. S., Bligh, John and Shopflocher, D. 1985. Long-term brain impairment in chronic alcoholics: N2-P3 cognitive potentials in a template-matching memory task. Alcohol and Alcoholism -London- Pergamon Press then Oxford University Press- 20 (4) , pp. 403-408.

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Abstract

Neuropsychological measurements and N2-P3 visual cognitive potentials evoked by a template-matching visual-memory task were collected from seemingly intact chronic alcoholics and normal controls. Psychometric results were not significantly different between alcoholics and controls, but the N2-P3 cognitive potentials of the alcoholic population showed a decreased amplitude and an atypical interhemispheric pattern of latencies that point to alcohol-related deficits. The different functional nature and possibly separate intracranial origin of N2 and P3 suggest respective cortical and hippocampal localisation of these deficits. Cognitive brain potentials were a more sensitive indicator of cerebral impairment than psychometric data

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > R Medicine (General)
Publisher:	Oxford University Press
ISSN:	0735-0414
Last Modified:	30 Jun 2017 03:24
URI:	https://orca.cardiff.ac.uk/id/eprint/56313

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