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DSM-5 Autism Spectrum Disorder: In search of essential behaviours for diagnosis

Carrington, Sarah J. ORCID:, Kent, Rachel Grace, Maljaars, Jarymke, Le Couteur, Ann, Gould, Judith, Wing, Lorna, Noens, Ilse, Van Berckelaer-Onnes, Ina and Leekam, Susan R. ORCID: 2014. DSM-5 Autism Spectrum Disorder: In search of essential behaviours for diagnosis. Research in Autism Spectrum Disorders 8 (6) , pp. 701-715. 10.1016/j.rasd.2014.03.017

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The objective of this study was to identify a set of ‘essential’ behaviours sufficient for diagnosis of DSM-5 Autism Spectrum Disorder (ASD). Highly discriminating, ‘essential’ behaviours were identified from the published DSM-5 algorithm developed for the Diagnostic Interview for Social and Communication Disorders (DISCO). Study 1 identified a reduced item set (48 items) with good predictive validity (as measured using receiver operating characteristic curves) that represented all symptom sub-domains described in the DSM-5 ASD criteria but lacked sensitivity for individuals with higher ability. An adjusted essential item set (54 items; Study 2) had good sensitivity when applied to individuals with higher ability and performance was comparable to the published full DISCO DSM-5 algorithm. Investigation at the item level revealed that the most highly discriminating items predominantly measured social-communication behaviours. This work represents a first attempt to derive a reduced set of behaviours for DSM-5 directly from an existing standardised ASD developmental history interview and has implications for the use of DSM-5 criteria for clinical and research practice.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Psychology
Subjects: B Philosophy. Psychology. Religion > BF Psychology
Uncontrolled Keywords: Autism spectrum disorder; DSM-5; Abbreviated; Diagnosis; DISCO
Publisher: Elsevier
ISSN: 1750-9467
Funders: ESRC, Wales Autism Research Centre Foundation Funding (led by Autism Cymru, Autistica and the Welsh Government)
Date of First Compliant Deposit: 30 March 2016
Last Modified: 11 May 2023 05:41

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