Key role of lipids in heat stress management

Balogh, Gábor, Péter, Mária, Glatz, Attila, Gombos, Imre, Török, Zsolt, Horváth, Ibolya, Harwood, John L. ORCID: https://orcid.org/0000-0003-2377-2612 and Vígh, László 2013. Key role of lipids in heat stress management. FEBS Letters 587 (13) , pp. 1970-1980. 10.1016/j.febslet.2013.05.016

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Abstract

Heat stress is a common and, therefore, an important environmental impact on cells and organisms. While much attention has been paid to severe heat stress, moderate temperature elevations are also important. Here we discuss temperature sensing and how responses to heat stress are not necessarily dependent on denatured proteins. Indeed, it is clear that membrane lipids have a pivotal function. Details of membrane lipid changes and the associated production of signalling metabolites are described and suggestions made as to how the interconnected signalling network could be modified for helpful intervention in disease.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Biosciences
Subjects:	Q Science > QH Natural history > QH301 Biology
Uncontrolled Keywords:	Heat stress; Mild heat exposure; Membrane lipid; Temperature sensing; Membrane sensor; Signalling network
Publisher:	Elsevier
ISSN:	0014-5793
Last Modified:	25 Oct 2022 09:34
URI:	https://orca.cardiff.ac.uk/id/eprint/59192

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