The effects of iron deficiency on rat liver enzymes

Bailey-Wood, R., Blayney, Lynda Mary, Muir, J. R. and Jacobs, A. 1975. The effects of iron deficiency on rat liver enzymes. British Journal of Experimental Pathology 56 (3) , pp. 193-198.

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Abstract

The effect of iron deficiency on a number or iron containing enzymes in rat liver has been examined. In addition, 6-phosphogluconate dehydrogenase and glucose 6-phosphate dehydrogenase have been assayed. Of the mitochondrial electron transport reactions only succinate-cytochrome C reductase activity was decreased in iron deficient animals. Microsomal reductase enzymes associated with the NADPH-oxidase system were also markedly decreased although cytochrome P450 concentrations were unaffected. Both 6-phosphogluconate dehydrogenase and glucose 6-phosphate dehydrogenase were reduced in young iron deficient rats but the former had returned to control levels at the age of 14 weeks.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > R Medicine (General)
Additional Information:	Continued as International Journal of Experimental Pathology
ISSN:	0007-1021
Last Modified:	31 Jan 2020 04:19
URI:	https://orca.cardiff.ac.uk/id/eprint/59390

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