Vitamin C supplementation of old people with low blood levels

Burr, Michael Leslie, Hurley, R. J. and Sweetnam, P. M. 1975. Vitamin C supplementation of old people with low blood levels. Gerontologia Clinica 17 (4) , pp. 236-243. 10.1159/000245583

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Abstract

Ascorbic acid blood levels were estimated in 828 elderly people living in the community. 297 subjects with low blood levels were admitted to a 2-year controlled trial of vitamin C. Despite a rise in plasma and leucocyte levels, vitamin C produced no apparent benefit in terms of mortality, morbidity or mental senescence. On following up all those who were originally seen, it was found that a higher proportion of deaths occurred among subjects whose leucocyte levels were below 15 μg/l08 cells than among the rest. This association was especially marked in the men; it was not due to smoking and was probably attributable to an effect of ill-health on blood levels, either directly or through impairment of appetite.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > R Medicine (General)
Publisher:	Karger
ISSN:	0016-8998
Last Modified:	04 May 2016 03:04
URI:	https://orca.cardiff.ac.uk/id/eprint/59545

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