Obstetric variables associated with bipolar affective puerperal psychosis

Robertson Blackmore, Emma, Jones, Ian Richard ORCID: https://orcid.org/0000-0001-5821-5889, Doshi, Monica, Haque, Syeed, Holder, Roger, Brockington, Ian and Craddock, Nicholas John ORCID: https://orcid.org/0000-0003-2171-0610 2006. Obstetric variables associated with bipolar affective puerperal psychosis. British Journal of Psychiatry 188 (1) , pp. 32-36. 10.1192/bjp.188.1.32

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Abstract

Background Previous cross-sectional studies have highlighted a number of obstetric variables that may be associated with the development of broadly defined puerperal (post-partum) psychosis. These include: (a) primiparity, (b) pregnancy complications, (c) delivery complications, (d) Caesarean section, (e) female baby and (f) shorter gestation period. Aims To examine these risk factors in women with well-characterised bipolar affective puerperal psychosis. Method A sample of 129 women with bipolar affective puerperal psychosis were investigated using a design that takes advantage of within-subject comparisons of affected and unaffected deliveries. Results Two of the variables studied were independently associated with an episode of puerperal psychosis: primiparity (odds ratio=3.76, P < 0.001) and delivery complications (odds ratio=2.68, P=0.022). Conclusions This study provides further evidence of the association between primiparity and puerperal psychosis and suggests that complications during delivery may be associated with a severe post-partum episode.

Item Type:	Article
Status:	Published
Schools:	Medicine MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG)
Subjects:	R Medicine > R Medicine (General)
Publisher:	Royal College of Psychiatrists
ISSN:	0007-1250
Last Modified:	27 Oct 2022 08:23
URI:	https://orca.cardiff.ac.uk/id/eprint/62146

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