Biological basis for the benefit of nutraceutical supplementation in arthritis

Curtis, Clare L., Harwood, John L. ORCID: https://orcid.org/0000-0003-2377-2612, Dent, Colin M. and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 2004. Biological basis for the benefit of nutraceutical supplementation in arthritis. Drug Discovery Today 9 (4) , pp. 165-172. 10.1016/S1359-6446(03)02980-5

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Abstract

Arthritis is a common disease in which the end-point results in joint replacement surgery. This article reviews the use of nutraceuticals as alternative treatments for pathological manifestations of arthritic disease. The efficacy of fish oils (e.g. cod liver oil) in the diet has been demonstrated in several clinical trials, animal feeding experiments and in vitro models that mimic cartilage destruction in arthritic disease. In addition, there is some evidence for beneficial effects of other nutraceuticals, such as green tea, herbal extracts, chondroitin sulphate and glucosamine. However, in most cases, there is little scientific evidence at the cellular and molecular levels to explain their mechanisms of action.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Biosciences
Additional Information:	This paper has an Erratum notice: Drug Discovery Today Volume 9, Issue 7, 1 April 2004, Page 336. https://doi.org/10.1016/S1359-6446(04)03052-1
Publisher:	Elsevier
ISSN:	13596446
Related URLs:	https://doi.org/10.1016/S1359-6446(04)03...
Last Modified:	03 Jun 2024 11:29
URI:	https://orca.cardiff.ac.uk/id/eprint/63313

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