Steroid receptors in the canine epididymis

Younes, M., Evans, Bronwen Alice James ORCID: https://orcid.org/0000-0002-3082-1008, Chaisiri, N., Valotaire, Y. and Pierrepoint, C. G. 1979. Steroid receptors in the canine epididymis. Reproduction 56 (1) , pp. 45-52. 10.1530/jrf.0.0560045

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Abstract

Summary. High-affinity and low-capacity molecules that bind 5α-dihydrotestosterone and oestradiol-17β have been demonstrated in the canine epididymis. The molecules were shown to be proteinaceous in nature, thermolabile and sedimented in a sucrose density gradient with a coefficient of 8S with respect to bovine serum albumin. Only minor differences were found for dissociation constants for oestradiol-17β (3·5 ± 2·74 × 10−10 m) and 5α-dihydrotestosterone (4·2 ± 10·75 × 10−10 m) (means ± s.d.) in the three anatomically distinct regions of the epididymis.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Schools > Medicine
Subjects:	R Medicine > R Medicine (General)
Publisher:	BioScientifica
ISSN:	1470-1626
Last Modified:	27 Oct 2022 09:26
URI:	https://orca.cardiff.ac.uk/id/eprint/65802

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