Use of sequential case-control studies to investigate a community Salmonella outbreak in Wales

Llewellyn, L. J., Evans, Meirion Rhys ORCID: https://orcid.org/0000-0003-3578-1866 and Palmer, Stephen Royston 1998. Use of sequential case-control studies to investigate a community Salmonella outbreak in Wales. Journal of Epidemiology & Community Health 52 (4) , pp. 272-276. 10.1136/jech.52.4.272

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Abstract

STUDY OBJECTIVE: To establish the source of a community outbreak of Salmonella typhimurium definitive type 124. DESIGN: Two stage case-control study. SETTING: Three districts in south east Wales. SUBJECTS: Cases of salmonella food poisoning and community controls. MAIN RESULTS: An initial case-control study identified an association between illness and eating ham (odds ratio 4.50, 95% confidence intervals 1.10, 21.8) and also found a possible association between illness and food bought from delicatessen stores (odds ratio 5.03, 95% confidence intervals 1.01, 32.3). However, only after a second stage case-control study was a single common ham producer identified as the source (odds ratio 25.0, 95% confidence intervals 2.33, 1155). CONCLUSION: Sequential case-control studies are an important and underused tool in the investigation of community outbreaks.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > R Medicine (General)
Publisher:	BMJ Publishing
ISSN:	0143-005x
Last Modified:	27 Oct 2022 09:40
URI:	https://orca.cardiff.ac.uk/id/eprint/67195

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