Highly sensitive detection of fungal antigens by ultrasound-enhanced latex agglutination

Grundy, M. A., Barnes, Rosemary Ann and Coakley, W. T. 1995. Highly sensitive detection of fungal antigens by ultrasound-enhanced latex agglutination. Journal of Medical and Veterinary Mycology 33 (3) , pp. 201-203. 10.1080/02681219580000411

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Abstract

Treatment with ultrasound has been employed to greatly enhance the sensitivity of commercially available latex agglutination tests for fungal antigens. This 5 min procedure detects 40 pg ml-1 of Candida albicans mannan and 70 pg ml-1 of Aspergillus fumigatus galactomannan, a 250 and 500-fold improvement respectively over conventional agglutination test sensitivities. The ultrasound-enhanced test offers the possibility of improved diagnosis and management of patients with systemical candidosis or invasive aspergillosis.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > R Medicine (General)
Publisher:	Informa Plc.
ISSN:	1369-3786
Last Modified:	04 Jun 2017 07:43
URI:	https://orca.cardiff.ac.uk/id/eprint/67334

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