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Microbial dehalogenation of trichloroacetic acid

Weightman, Alison Lesley ORCID:, Weightman, Andrew John ORCID: and Slater, J.Howard 1992. Microbial dehalogenation of trichloroacetic acid. World Journal of Micorobiology & Biotechnology 8 (5) , pp. 512-518. 10.1007/BF01201951

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A pure bacterial culture and a two-membered mixed culture were isolated that degraded trichloroacetic acid if a second, readily metabolizable substrate was present in the growth medium. Previous doubts over the microbial dehalogenation of trichloroacetic acid (TCA) may be due to its inability to act as a sole carbon and energy source. TCA dehalogenation was associated with conventional 2-haloalkanoic acid dehalogenases but oxalate, the putative dehalogenase product, was not detected. CO z was produced rapidly and concomitantly with CI-ion release during dehalogenation of TCA. An alternative mechanism is suggested for TCA dehalogenation via an initial decarboxylation reaction. This mechanism predicts that carbon monoxide is a product of TCA decarboxylation and it was significant that one of the organisms isolated, Pseudomonas carboxydohydrogens, was a carboxytroph and a second was an unidentified facultative methylotroph.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Biosciences
Academic & Student Support Service
Uncontrolled Keywords: Dehalogenases; dehalogenation; methylotrophs; Pseudomonas; trichloroacetic acid
Publisher: Rapid Science Publishers
ISSN: 0959-3993
Last Modified: 17 Oct 2022 10:06

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