| Wallace, Marina, Frayling, Ian, Clark, Susan, Neale, Kay and Phillips, Robin K. S. 1999. Attenuated adenomatous polyposis coli - The role of ascertainment bias through failure to dye-spray at colonoscopy. Diseases of the Colon & Rectum 42 (8) , pp. 1078-1080. 10.1007/BF02236707 |
Abstract
PURPOSE: The aim of this study is to show that the diagnosis of attenuated adenomatous polyposis coli must be made with caution and certainly only after adequate colonic examination with dye-spray. METHODS: Four patients thought to have attenuated adenomatous polyposis coli on the basis of family history and the identification of fewer than 100 polyps on simple colonoscopy underwent colonoscopy with dye-spray. RESULTS: All four individuals were found to have more than 100 polyps when dye-spray was used, confirming a diagnosis of classical familial adenomatous polyposis. CONCLUSIONS: The diagnosis of familial adenomatous polyposis may be missed altogether or incorrectly assigned as attenuated adenomatous polyposis coli if dye-spray is not used at colonoscopy. Patients with a family history of familial adenomatous polyposis or colorectal cancer should be considered for dye-spray before the diagnosis of familial adenomatous polyposis is excluded or one of attenuated adenomatous polyposis coli is made.
| Item Type: | Article |
|---|---|
| Date Type: | Publication |
| Status: | Published |
| Schools: | Schools > Medicine |
| Subjects: | R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer) |
| Additional Information: | Presented at the Eighth Biennial meeting of the Leeds Castle Polyposis Group, Lorne, Australia, March 1 to 6, 1999. |
| Publisher: | Springer |
| Funders: | Imperial Cancer Research Fund |
| Last Modified: | 04 Jun 2017 07:56 |
| URI: | https://orca.cardiff.ac.uk/id/eprint/70131 |
Citation Data
Cited 42 times in Scopus. View in Scopus. Powered By Scopus® Data
Actions (repository staff only)
 |
Edit Item |
Altmetric
Altmetric