Desmoid precursor lesions [Abstract]

Clark, S. K., Johnson-Smith, T. G. P., Katz, D. E., Reznek, R. H., Frayling, Ian Martin and Phillips, R. K.S. 1998. Desmoid precursor lesions [Abstract]. British Journal of Surgery 85 (5) , p. 711. 10.1046/j.1365-2168.1998.00794.x

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Abstract

Background: Germline mutations of the APC tumour suppressor gene on chromosome 5q22 are responsible for familial adeno- matous polyposis (FAP). Desmoid tumours are poorly under- stood, locally invasive, non-metastasizing neoplasms that occur in about 10 per cent of patients with FAP. The natural history of desmoids was investigated by documenting prospectively the prevalence and progression of possible precursor lesions, and comparing the somatic genetics of these with established desmoid tumours.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Additional Information:	Surgical Research Society abstracts
Publisher:	Wiley-Blackwell
ISSN:	0007-1323
Last Modified:	04 Jun 2017 07:56
URI:	https://orca.cardiff.ac.uk/id/eprint/70137

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