Endothelial function and dysfunction. Part I: methodological issues for assessment in the different vascular beds: a statement by the Working Group on Endothelin and Endothelial Factors of the European Society of Hypertension

Deanfield, John, Donald, Ann, Ferri, Claudio, Giannattasio, Cristina, Halcox, Julian, Halligan, Sean, Lerman, Amir, Mancia, Giuseppe, Oliver, James J., Pessina, Achille C., Rizzoni, Damiano, Rossi, Gian Paolo, Salvetti, Antonio, Schiffrin, Ernesto L., Taddei, Stefano and Webb, David J. 2005. Endothelial function and dysfunction. Part I: methodological issues for assessment in the different vascular beds: a statement by the Working Group on Endothelin and Endothelial Factors of the European Society of Hypertension. Journal of Hypertension 23 (1) , pp. 7-17. 10.1097/00004872-200501000-00004

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Abstract

An enormous number of studies in the last two decades have been devoted to investigating the role of the endothelium in cardiovascular diseases. Nonetheless, the optimal methodology for investigating the multifaceted aspects of endothelial dysfunction is still under debate. Biochemical markers, molecular genetic tests and invasive and non-invasive tools with and without pharmacological and physiological stimuli have been introduced. Furthermore newer pharmacological tools have been proposed. However, the application of these methodologies should fulfil a number of requirements in order to provide conclusive answers in this area of research. Thus, the most relevant methodological issues in the research on endothelial function and dysfunction are summarized in this paper.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Schools > Medicine
Subjects:	R Medicine > R Medicine (General)
Additional Information:	Full Text Sources Lippincott Williams & Wilkins Ovid Technologies, Inc. Other Literature Sources COS Scholar Universe Labome Researcher Resource - ExactAntigen/Labome Access more work from the authors - ResearchGate Medical ClinicalTrials.gov High Blood Pressure - MedlinePlus Health Information
Publisher:	Lippincott Williams & Wilkins
ISSN:	0263-6352
Date of Acceptance:	8 September 2004
Last Modified:	02 Nov 2015 11:11
URI:	https://orca.cardiff.ac.uk/id/eprint/71066

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