ADHD severity is associated with white matter microstructure in the subgenual cingulum

Cooper, Miriam ORCID: https://orcid.org/0000-0002-4695-5481, Thapar, Anita ORCID: https://orcid.org/0000-0002-3689-737X and Jones, Derek K. ORCID: https://orcid.org/0000-0003-4409-8049 2015. ADHD severity is associated with white matter microstructure in the subgenual cingulum. NeuroImage: Clinical 7 , pp. 653-660. 10.1016/j.nicl.2015.02.012

Preview

PDF Available under License Creative Commons Attribution. Download (809kB) | Preview

Abstract

This analysis examined hypothesised associations between microstructural attributes in specific white matter (WM) tracts selected a priori and measures of clinical variability in adolescents with a diagnosis of attention deficit hyperactivity disorder (ADHD). Firstly, associations were explored between WM microstructure and ADHD severity in the subgenual cingulum. Secondly, to ensure that tract-specific approaches afforded enhanced rather than differential sensitivity, associations were measured between WM microstructure and autistic traits in the right corticospinal tract based on results of a previously-published voxelwise analysis.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Psychology Medicine Neuroscience and Mental Health Research Institute (NMHRI) Cardiff University Brain Research Imaging Centre (CUBRIC) MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG)
Subjects:	R Medicine > R Medicine (General) R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Uncontrolled Keywords:	Attention deficit hyperactivity disorder (ADHD); Autism spectrum disorder (ASD); Diffusion MRI; White matter; Spherical deconvolution; Tractography
Publisher:	Elsevier
ISSN:	2213-1582
Funders:	Wellcome Trust
Date of First Compliant Deposit:	30 March 2016
Date of Acceptance:	22 February 2015
Last Modified:	07 May 2023 20:36
URI:	https://orca.cardiff.ac.uk/id/eprint/72922

Citation Data

Cited 19 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item