Neutrophil priming by hepatocyte growth factor, a novel cytokine

Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111, Puntis, M. C., Nakamura, T. and Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X 1992. Neutrophil priming by hepatocyte growth factor, a novel cytokine. Immunology 77 (1) , pp. 147-149.

Full text not available from this repository.

Abstract

We demonstrate here that the recently defined cytokine hepatocyte growth factor (HGF) 'primes' human neutrophils. Recombinant human HGF over the concentration range 0.1-20 ng/ml increased the neutrophil response to f-met-leu-phe by up to 200%, and required only a short preincubation, 10 min producing the maximum effect. Priming was independent of changes in cytosolic-free calcium homeostasis. We conclude that HGF may be a physiologically important cytokine with 'priming' activity for neutrophils

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Schools > Medicine
Subjects:	R Medicine > R Medicine (General)
Publisher:	Wiley Blackwell
ISSN:	0019-2805
Related URLs:	http://www.ncbi.nlm.nih.gov/entrez/query...
Last Modified:	28 Oct 2022 09:04
URI:	https://orca.cardiff.ac.uk/id/eprint/73184

Citation Data

Cited 29 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item