Feasibility of using biomarkers in blood serum as markers of effect following exposure of the lungs to particulate matter air pollution [review]

Elvidge, Timothy, Matthews, Ian Price, Gregory, Clive ORCID: https://orcid.org/0000-0003-4876-3982 and Hoogendoorn, Bastiaan ORCID: https://orcid.org/0000-0001-9753-169X 2013. Feasibility of using biomarkers in blood serum as markers of effect following exposure of the lungs to particulate matter air pollution [review]. Journal of Environmental Science and Health, Part C 31 (1) , pp. 1-44. 10.1080/10590501.2013.763575

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Abstract

Particulate matter (PM) air pollution has significant cardiopulmonary health effects. Serum biomarkers may elucidate the disease mechanisms involved and provide a means for biomonitoring exposed populations, thereby enabling accurate policy decisions on air quality standards to be made. For this review, research investigating association of blood serum biomarkers and exposure to PM was identified, finding 26 different biomarkers that were significantly associated with exposure. Recent evidence links different effects to different components of PM. Future research on biomarkers of effect will need to address exposure by all PM size fractions.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > R Medicine (General) R Medicine > RC Internal medicine R Medicine > RZ Other systems of medicine
Uncontrolled Keywords:	air pollution; epidemiologic studies; exposure assessment; human health effects; oxidative stress; particulate matter; serum biomarkers
Publisher:	Taylor & Francis
ISSN:	1059-0501
Last Modified:	16 Nov 2022 07:42
URI:	https://orca.cardiff.ac.uk/id/eprint/76107

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