Directed therapy for fungal infections: focus on aspergillosis

Barnes, Rosemary Ann 2013. Directed therapy for fungal infections: focus on aspergillosis. Journal of Antimicrobial Chemotherapy 68 (11) , pp. 2431-2434. 10.1093/jac/dkt227

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Abstract

Directed therapy aims to target antifungal drugs to patients most likely to have fungal disease and to reduce the use of empirical therapy. The term embraces both pre-emptive therapy, where biomarkers are used to detect early signs of infection before there is clinical disease, and diagnostically driven approaches, which rely on radiological signs to detect early manifestations of clinical disease. Better targeting of drugs can potentially reduce antifungal expenditure, limit the development of resistance and improve outcomes for patients. © The Author 2013. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > R Medicine (General) R Medicine > RZ Other systems of medicine
Uncontrolled Keywords:	Antifungal Agents; Aspergillosis; Drug Resistance, Fungal; Drug Utilization; Humans
Publisher:	Oxford University Press
ISSN:	0305-7453
Last Modified:	04 Jun 2017 08:21
URI:	https://orca.cardiff.ac.uk/id/eprint/76339

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