Jones, Lim S., Toleman, Mark A. ORCID: https://orcid.org/0000-0002-9497-0512, Weeks, Janis L., Howe, Robin A., Walsh, Timothy R. ORCID: https://orcid.org/0000-0003-4315-4096 and Kumarasamy, Karthikeyan K. 2014. Plasmid carriage of blaNDM-1 in clinical Acinetobacter baumannii isolates from India. Antimicrobial Agents and Chemotherapy 58 (7) , pp. 4211-4213. 10.1128/AAC.02500-14 |
Official URL: http://dx.doi.org/10.1128/AAC.02500-14
Abstract
NDM-1 probably emerged in Acinetobacter species prior to its dissemination among Enterobacteriaceae, and NDM-1-like enzymes are increasingly reported in Acinetobacter species. Here, we report on the genetic context of blaNDM-1 in the earliest known NDM-1-producing organisms, clinical isolates of Acinetobacter from India in 2005. These strains harbor blaNDM-1 plasmids of different sizes. The gene is associated with the remnants of the Tn125 transposon normally associated with blaNDM-1 in Acinetobacter spp. The transposon has been disrupted by the IS26 insertion and subsequent movement events.
Item Type: | Article |
---|---|
Date Type: | Publication |
Status: | Published |
Schools: | Medicine Systems Immunity Research Institute (SIURI) |
Subjects: | Q Science > QR Microbiology |
Publisher: | American Society for Microbiology |
ISSN: | 0066-4804 |
Date of Acceptance: | 13 April 2014 |
Last Modified: | 28 Oct 2022 10:28 |
URI: | https://orca.cardiff.ac.uk/id/eprint/78421 |
Citation Data
Cited 37 times in Scopus. View in Scopus. Powered By Scopus® Data
Actions (repository staff only)
Edit Item |