Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

AINTEGUMENTA and the D-type cyclin CYCD3;1 regulate root secondary growth and respond to cytokinins

Randall, Ricardo ORCID:, Miyashima, Shunsuke, Blomster, Tiina, Zhang, Jing, Elo, Annakaisa, Karlberg, Anna, Immanen, Juha, Nieminen, Kaisa, Lee, Ji-Young, Kakimoto, Tatsuo, Blajecka, Karolina, Melnyk, Charles W., Alcasbas, Annette, Forzani, Celine, Matsumoto-Kitano, Miho, Mähönen, Ari Pekka, Bhalerao, Rishikesh, Dewitte, Walter ORCID:, Helariutta, Ykä and Murray, James Augustus Henry ORCID: 2015. AINTEGUMENTA and the D-type cyclin CYCD3;1 regulate root secondary growth and respond to cytokinins. Biology Open 4 , pp. 1229-1236. 10.1242/bio.013128

[thumbnail of murray 2015.pdf]
PDF - Published Version
Available under License Creative Commons Attribution.

Download (1MB) | Preview


Higher plant vasculature is characterized by two distinct developmental phases. Initially, a well-defined radial primary pattern is established. In eudicots, this is followed by secondary growth, which involves development of the cambium and is required for efficient water and nutrient transport and wood formation. Regulation of secondary growth involves several phytohormones, and cytokinins have been implicated as key players, particularly in the activation of cell proliferation, but the molecular mechanisms mediating this hormonal control remain unknown. Here we show that the genes encoding the transcription factor AINTEGUMENTA (ANT) and the D-type cyclin CYCD3;1 are expressed in the vascular cambium of Arabidopsis roots, respond to cytokinins and are both required for proper root secondary thickening. Cytokinin regulation of ANT and CYCD3 also occurs during secondary thickening of poplar stems, suggesting this represents a conserved regulatory mechanism.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Biosciences
Subjects: Q Science > QH Natural history > QH301 Biology
Publisher: The Company of Biologists
ISSN: 2046-6390
Funders: BBSRC
Date of First Compliant Deposit: 30 March 2016
Date of Acceptance: 5 August 2015
Last Modified: 15 May 2023 15:57

Citation Data

Cited 70 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item


Downloads per month over past year

View more statistics