Modelling the occurrence and pathology of Alzheimer's disease

Hardy, J.A., Goate, A.M., Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, Mullan, M.J., Rossor, M.N. and Pearson, R.C.A. 1989. Modelling the occurrence and pathology of Alzheimer's disease. Neurobiology of Aging 10 (5) , pp. 429-431. 10.1016/0197-4580(89)90084-5

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Abstract

Our work has confirmed that of St. George-Hyslop and colleagues, suggesting FAD linkage to the short arm of chromosome 21 in outbred families with a presenile onset of the disease. Future genetic studies should help clarify the current apparent discrepancies between certain laboratories and ultimately lead to a better understanding of the variables which predispose individuals to the disease.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG) Medicine Neuroscience and Mental Health Research Institute (NMHRI)
Subjects:	R Medicine > R Medicine (General)
Publisher:	Elsevier
ISSN:	0197-4580
Last Modified:	31 Oct 2022 09:28
URI:	https://orca.cardiff.ac.uk/id/eprint/81139

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