Neurodegenerative diseases of Guam: analysis of TAU

Perez-Tur, J., Buee, L., Morris, Huw, Waring, S. C., Onstead, L., Wavrant-De Vrieze, F., Crook, R., Buee-Scherrer, V., Hof, P. R., Peterson, R. C., McGeer, P. L., Delacourte, A., Hutton, M., Siddique, T., Ahlskog, J. E., Hardy, J. and Steele, J. C. 1999. Neurodegenerative diseases of Guam: analysis of TAU. Neurology 53 (2) , pp. 411-413. 10.1212/WNL.53.2.411

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Abstract

Mutations in the tau gene have been described in families affected by frontotemporal dementia with parkinsonism linked to chromosome 17. The authors performed a genetic and biochemical analysis of this gene and its product in the parkinsonism dementia complex of Guam, a disorder characterized by the extensive formation of neurofibrillary tangles. The tau gene is not a primary cause of the parkinsonism dementia complex of Guam.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Publisher:	Lippincott Williams & Wilkins
ISSN:	0028-3878
Last Modified:	26 Nov 2015 15:22
URI:	https://orca.cardiff.ac.uk/id/eprint/81409

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