Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Factor-derived subsyndromes of schizophrenia and familial morbid risks

Cardno, Alastair, Holmans, Peter Alan ORCID:, Harvey, I., Williams, M. B., Owen, Michael John ORCID: and McGuffin, P. 1996. Factor-derived subsyndromes of schizophrenia and familial morbid risks. Schizophrenia Research 18 (2-3) , IVA2-IVA2.

Full text not available from this repository.


Factor analysis was performed on OPCRIT checklist ratings from 66 patients with RDC schizophrenia. Eight substantive factors were found, characterised respectively by: positive formal thought disorder; first rank delusions; first rank hallucinations; inappropriate affect/bizarre behaviour; negative symptoms; grandiose/bizarre delusions; delusions of influence/persecution; and other hallucinations. A history of schizophrenia and other non-affective psychoses was ascertained in the probands' first-degree relatives using a family history approach. Illness in relatives was best predicted by probands' scores on subsyndromes derived from the inappropriate affect/bizarre behaviour and positive formal thought disorder factors.

Item Type: Article
Date Type: Publication
Status: Published
Schools: MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG)
Neuroscience and Mental Health Research Institute (NMHRI)
Subjects: R Medicine > R Medicine (General)
Publisher: Elsevier
ISSN: 0920-9964
Last Modified: 31 Oct 2022 09:35

Actions (repository staff only)

Edit Item Edit Item