No evidence for an allelic association between schizophrenia and markers D22S278 and D22S283

Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Jones, L. A., Murphy, K. C., Cardno, A. G., Asherson, P., Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259, McGuffin, P. and Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 1997. No evidence for an allelic association between schizophrenia and markers D22S278 and D22S283. American Journal of Medical Genetics 74 (1) , pp. 37-39. 10.1002/(SICI)1096-8628(19970221)74:1<37::AID-AJMG8>3.0.CO;2-S

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Abstract

We report a case control association study using markers D22S278 and D22S283 in 90 unrelated patients with DSMIII-R schizophrenia and 90 controls matched for ethnicity, age and sex. No differences between allele frequencies for either marker were observed when the two groups were compared (D22S278: chi 2 = 6.53, df = 7, P = 0.51; D22S283: chi 2 = 14.73, df = 15, P = 0.48). These findings fail to support previous work by others suggesting the presence of allelic association between the markers D22S278 and D22S283 and schizophrenia.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Schools > Medicine Research Institutes & Centres > MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG) Research Institutes & Centres > Neuroscience and Mental Health Research Institute (NMHII)
Subjects:	R Medicine > R Medicine (General)
Publisher:	Wiley
ISSN:	0148-7299
Last Modified:	25 Oct 2024 01:24
URI:	https://orca.cardiff.ac.uk/id/eprint/81904

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