The incidence and prevalence of diabetes in patients with serious mental illness in North West Wales: Two cohorts, 1875-1924 & 1994-2006 compared

Le Noury, Joanna, Khan, Afshan, Harris, Margaret, Wong, Winnie, Williams, Dawn, Roberts, Tony, Tranter, Richard and Healy, David 2008. The incidence and prevalence of diabetes in patients with serious mental illness in North West Wales: Two cohorts, 1875-1924 & 1994-2006 compared. BMC Psychiatry 8 (1) , 67. 10.1186/1471-244X-8-67

Preview

PDF - Published Version Available under License Creative Commons Attribution. Download (196kB) | Preview

Abstract

BACKGROUND: Against a background of interest in rates of diabetes in schizophrenia and related psychoses and claims that data from historical periods demonstrate a link that antedates modern antipsychotics, we sought to establish the rate of diabetes in first onset psychosis and subsequent prevalence in historical and contemporary cohorts. METHODS: Analysis of two epidemiologically complete databases of individuals admitted for mental illness. 3170 individuals admitted to the North Wales Asylum between 1875-1924 and tracked over 18,486 patient years and 394 North West Wales first admissions for schizophrenia and related psychoses between 1994 and 2006 and tracked after treatment. RESULTS: The prevalence of Type 2 diabetes among patients with psychoses at time of first admission in both historical and contemporary samples was 0%. The incidence of diabetes remained 0% in the historical sample throughout 15 years of follow-up but rose in the contemporary sample after 3, 5 and 6 years of treatment with an incidence rate double the expected population rate so that the 15 year prevalence is likely to be over 8%. CONCLUSION: No association was found between diabetes and serious mental illness, but there may be an association between diabetes and treatment.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > R Medicine (General)
Publisher:	BioMed Central
ISSN:	1471-244X
Date of First Compliant Deposit:	21 August 2018
Last Modified:	06 May 2023 03:41
URI:	https://orca.cardiff.ac.uk/id/eprint/82053

Citation Data

Cited 14 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item