Compact, low-cost Ti:Al_2O_3 laser for in vivo ultrahigh-resolution optical coherence tomography

Unterhuber, A., Povazay, B., Hermann, B., Sattmann, H., Drexler, W., Yakovlev, V., Tempea, G., Schubert, C., Anger, E. M., Ahnelt, P. K., Stur, M., Morgan, James Edwards ORCID: https://orcid.org/0000-0002-8920-1065, Cowey, A., Jung, G., Le, T. and Stingl, A. 2003. Compact, low-cost Ti:Al_2O_3 laser for in vivo ultrahigh-resolution optical coherence tomography. Optics Letters 28 (11) , pp. 905-907. 10.1364/OL.28.000905

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Abstract

A compact, low-cost, prismless Ti:Al2O3 laser with 176-nm bandwidth (FWHM) and 20-mW output power was developed. Ultrahigh-resolution ophthalmic optical coherence tomography (OCT) ex vivo imaging in an animal model with approximately 1.2-microm axial resolution and in vivo imaging in patients with macular pathologies with approximately 3-microm axial resolution were demonstrated. Owing to the pump laser, this light source significantly reduces the cost of broadband OCT systems. Furthermore, the source has great potential for clinical application of spectroscopic and ultrahigh-resolution OCT because of its small footprint (500 mm x 180 mm including the pump laser), user friendliness, stability, and reproducibility.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > R Medicine (General)
ISSN:	0146-9592
Last Modified:	31 Oct 2022 09:44
URI:	https://orca.cardiff.ac.uk/id/eprint/82280

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