Sex hormones: a role in the control of multiple sclerosis?

Tomassini, Valentina ORCID: https://orcid.org/0000-0002-7368-6280 and Pozzilli, Carlo 2006. Sex hormones: a role in the control of multiple sclerosis? Expert Opinion on Pharmacotherapy 7 (7) , pp. 857-868. 10.1517/14656566.7.7.857

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Abstract

Several lines of evidence suggest that gender affects the susceptibility and course of multiple sclerosis. A higher disease prevalence, as well as an overall better prognosis, in women than men is observed. This sex dimorphism may be explained by the effect of sex hormones on brain damage and repair mechanisms. Experimental, clinical and MRI evidence confirms a pathogenetic link between sex hormones and multiple sclerosis, also suggesting sex-specific effects of hormones in multiple sclerosis pathology and therapy. A gender-based approach to multiple sclerosis could provide further benefits for its treatment and management.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG)
Subjects:	R Medicine > R Medicine (General)
Publisher:	Informa Healthcare
ISSN:	1465-6566
Last Modified:	31 Oct 2022 09:47
URI:	https://orca.cardiff.ac.uk/id/eprint/82462

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