'Gender gap' in multiple sclerosis: magnetic resonance imaging evidence

Pozzilli, C., Tomassini, Valentina ORCID: https://orcid.org/0000-0002-7368-6280, Marinelli, F., Paolillo, A., Gasperini, C. and Bastianello, S. 2003. 'Gender gap' in multiple sclerosis: magnetic resonance imaging evidence. European Journal of Neurology 10 (1) , pp. 95-97. 10.1046/j.1468-1331.2003.00519.x

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Abstract

The authors evaluated the gender difference in the magnetic resonance imaging characteristics of the lesions occurring in the brain of 413 multiple sclerosis (MS) patients. Men had fewer contrast-enhancing lesions (P = 0.01), but a higher proportion of lesions evolving into 'black holes' (P = 0.001), when compared with women. Thus, our data indicate that men with MS are prone to develop less inflammatory, but more destructive lesions than women. This study results provides support for a modulation of the MS pathological changes by gender.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG) Medicine
Subjects:	R Medicine > R Medicine (General)
Publisher:	Wiley
ISSN:	1351-5101
Last Modified:	31 Oct 2022 09:53
URI:	https://orca.cardiff.ac.uk/id/eprint/82813

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