Adenoviral vectors in gene therapy

Pjechová, Mariana, Hernychová, Lenka, Tomasec, Peter, Wilkinson, Gavin ORCID: https://orcid.org/0000-0002-5623-0126 and Vojtěšek, B. 2015. Adenoviral vectors in gene therapy. Klinicka onkologie 28 (Suppl) , 2S75-2S80. 10.14735/amko20152S75

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Abstract

This review is focused on gene therapy, especially adenovirus vectors and their relationship with the immune system response. Adenovirus vectors belong to the most used gene delivery vehicles in gene therapy, study of gene expression or immunotherapy. One of the most important questions concerning their use is their influence on organism in vivo. Study of immunomodulating properties of the adenovirus vectors opens a way for further manipulation and their more effective practical use.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > R Medicine (General)
Uncontrolled Keywords:	gene therapy, adenoviridae, immune system
Publisher:	Brno : Ceská lékarská spolecnost
ISSN:	0862-495X
Date of Acceptance:	20 July 2015
Last Modified:	31 Oct 2022 10:39
URI:	https://orca.cardiff.ac.uk/id/eprint/85603

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