Microbiome manipulation with faecal microbiome transplantation as a therapeutic strategy in Clostridium difficile infection

Mullish, B. H., Marchesi, Julian Roberto ORCID: https://orcid.org/0000-0002-7994-5239, Thursz, M. R. and Williams, H. R. T. 2015. Microbiome manipulation with faecal microbiome transplantation as a therapeutic strategy in Clostridium difficile infection. QJM: An International Journal of Medicine 108 (5) , pp. 355-359. 10.1093/qjmed/hcu182

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Abstract

Faecal microbiome transplantation (FMT) has generated huge recent interest as it presents a potential solution to a significant clinical problem—the increasing incidence of Clostridium difficile infection (CDI). In the short term, however, there remain many practical questions regarding its use, including the optimal selection of donors, material preparation and the mechanics of delivery. In the longer term, enhanced understanding of the mechanisms of action of FMT may potentiate novel therapies, such as targeted manipulation of the microbiome in CDI and beyond.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Biosciences
Subjects:	Q Science > QR Microbiology
Publisher:	Oxford University Press
ISSN:	1460-2725
Date of First Compliant Deposit:	30 March 2016
Last Modified:	22 Nov 2024 02:00
URI:	https://orca.cardiff.ac.uk/id/eprint/86807

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