Relationship between measurements of non-HDL-cholesterol and LDL-cholesterol in Familial Hypercholesterolaemia

Abreu, J., Haralambos, Kate ORCID: https://orcid.org/0000-0001-6075-3125, Ashfield-Watt, Pauline Annie L., Edwards, R., Gingell, R., Townsend, D., Datta, D. and McDowell, Ian Frederick 2016. Relationship between measurements of non-HDL-cholesterol and LDL-cholesterol in Familial Hypercholesterolaemia. Atherosclerosis 245 , e247. 10.1016/j.atherosclerosis.2015.10.037

Full text not available from this repository.

Abstract

Familial Hypercholesterolaemia (FH) is a monogenic disorder of Low Density Lipoprotein (LDL) metabolism which can be specifically diagnosed by genetic testing. However LDL-cholesterol (LDL-C) estimation has the drawback that it requires a fasting sample, because the Friedewald formula uses a factor relating to fasting triglyceride. Also other cholesterol containing lipoproteins are atherogenic and should be considered as part of cardiovascular risk assessment. Recent guidelines from National Institute for Health and Care Excellence (NICE) recommend non-HDL cholesterol (non HDL-C) for assessment of cardiovascular risk.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > R Medicine (General)
Publisher:	Elsevier
ISSN:	0021-9150
Last Modified:	31 Oct 2022 11:01
URI:	https://orca.cardiff.ac.uk/id/eprint/87088

Actions (repository staff only)

Edit Item