A quantitative and qualitative evaluation of LISA, a decision support system for chemotherapy dosing in childhood acute lymphoblastic leukaemia

Bury, J., Hurt, Chris Nicholas ORCID: https://orcid.org/0000-0003-1206-8355, Roy, A., Bradburn, M., Cross, S., Fox, J. and Saha, V. 2004. A quantitative and qualitative evaluation of LISA, a decision support system for chemotherapy dosing in childhood acute lymphoblastic leukaemia. Fieschi, M., Coiera, E. and Yu-Chan, J. L., eds. MEDINFO 2004, Vol. 107. Studies in Health Technology and Informatics, IOS Press, pp. 197-201. (10.3233/978-1-60750-949-3-197)

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Abstract

Objectives: To assess the acceptability to clinicians of a webbased decision support system designed to assist with dosage adjustments during maintenance therapy for childhood Acute Lymphoblastic Leukaemia (ALL), and to evaluate the potential impact of the system on decision-making and dosage calculations. Design: Balanced-block crossover experiment with simulated cases; questionnaire study and semi-structured interviews. Participants: 36 clinicians with differing experience in the management of ALL. Interventions: Subjects were asked to decide on appropriate levels of chemotherapy dosing for 8 simulated cases, 4 using the LISA decision support system, 4 using conventional paper-based records and guidance. Main outcome measures: Number of protocol-consistent dosage decisions made; time taken to manage each case; accuracy of dosage calculations; subjects' opinions as to whether or not they would use the system in practice. Additional outcome measures: Functions subjects would like to see in an idealised system; subjects’satisfaction with the implementation of the functions provided by LISA; qualitative data on issues subjects felt would impact upon the successful deployment of the system.

Item Type:	Book Section
Status:	Published
Schools:	Biosciences Medicine
Publisher:	IOS Press
Funders:	CRUK
Last Modified:	01 Nov 2022 10:06
URI:	https://orca.cardiff.ac.uk/id/eprint/90247

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