Preparation, loading, and cytotoxicity analysis of polymer nanotubes from an ethylene glycol dimethacrylate homopolymer in comparison to multi-walled carbon nanotubes

Newland, Benjamin ORCID: https://orcid.org/0000-0002-5214-2604, Thomas, Laurent, Zheng, Yu, Steinhart, Martin, Werner, Carsten and Wang, Wenxian 2016. Preparation, loading, and cytotoxicity analysis of polymer nanotubes from an ethylene glycol dimethacrylate homopolymer in comparison to multi-walled carbon nanotubes. Journal of Interdisciplinary Nanomedicine 1 (1) , pp. 9-18. 10.1002/jin2.7

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Abstract

Despite concerns over toxicity, carbon nanotubes have been extensively investigated for potential applications in nanomedicine because of their small size, unique properties, and ability to carry cargo such as small molecules and nucleic acids. Herein, we show that polymer nanotubes can be synthesized quickly and easily from a homopolymer of ethylene glycol dimethacrylate (EGDMA). The nanotubes formed via photo-initiated polymerization of the highly functional prepolymer, inside an anodized aluminium oxide template, have a regular structure and large internal pore and can be loaded with a fluorescent dye within minutes representing a simple alternative to multi-walled carbon nanotubes for biomedical applications.

Item Type:	Article
Date Type:	Published Online
Status:	Published
Schools:	Biosciences Pharmacy
Publisher:	Wiley
ISSN:	20583273
Funders:	Wellcome trust
Date of First Compliant Deposit:	19 May 2016
Date of Acceptance:	9 December 2015
Last Modified:	05 May 2023 02:46
URI:	https://orca.cardiff.ac.uk/id/eprint/91053

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